Jian-Zhi Wang Selected Research

Synapsins (Synapsin I)

11/2018	Methanolic extract of Tamarix Gallica attenuates hyperhomocysteinemia induced AD-like pathology and cognitive impairments in rats.
1/2015	Fluorocitrate induced the alterations of memory-related proteins and tau hyperphosphorylation in SD rats.
2/2013	Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.
1/2012	Pesticides induce spatial memory deficits with synaptic impairments and an imbalanced tau phosphorylation in rats.

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Jian-Zhi Wang Research Topics

Disease

127	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 03/2002
42	Memory Disorders (Memory Loss) 04/2024 - 06/2007
38	Cognitive Dysfunction 04/2024 - 11/2009
25	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2024 - 03/2002
21	Tauopathies 01/2024 - 08/2002
13	Hyperhomocysteinemia 01/2020 - 04/2009
12	Amyloid Plaque 04/2024 - 09/2012
10	Neuroblastoma 03/2024 - 04/2004
8	Dementia (Dementias) 01/2023 - 11/2007
4	Type 2 Diabetes Mellitus (MODY) 09/2023 - 01/2021
4	Schizophrenia (Dementia Praecox) 02/2023 - 06/2011
4	Inflammation (Inflammations) 10/2022 - 07/2013
3	Neoplasms (Cancer) 01/2022 - 10/2015
3	Neuroinflammatory Diseases 12/2020 - 01/2016
2	Parkinson Disease (Parkinson's Disease) 02/2024 - 08/2017
2	Frontotemporal Dementia (Semantic Dementia) 01/2023 - 08/2002
2	Mitochondrial Diseases (Mitochondrial Disease) 12/2020 - 06/2018
2	Mental Disorders (Mental Disorder) 01/2020 - 01/2017
2	Infections 01/2019 - 01/2014
2	Hypertension (High Blood Pressure) 11/2017 - 03/2016
2	Wounds and Injuries (Trauma) 04/2014 - 07/2009
2	Insulin Resistance 04/2014 - 01/2014
2	Brain Ischemia (Cerebral Ischemia) 10/2010 - 07/2009
2	Hypoxia (Hypoxemia) 08/2007 - 09/2005

Drug/Important Bio-Agent (IBA)

40	Proteins (Proteins, Gene)FDA Link 04/2024 - 03/2002
31	Amyloid (Amyloid Fibrils)IBA 04/2024 - 08/2006
14	Glycogen Synthase (Synthase I)IBA 09/2023 - 01/2007
13	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2020 - 08/2004
13	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2020 - 09/2004
12	tau Proteins (tau Protein)IBA 02/2024 - 10/2009
11	Biomarkers (Surrogate Marker)IBA 12/2022 - 11/2009
9	asparaginylendopeptidase (legumain)IBA 01/2021 - 11/2014
9	MelatoninIBA 07/2013 - 02/2002
8	HomocysteineIBA 03/2024 - 01/2011
8	Amyloid beta-PeptidesIBA 02/2024 - 08/2006
7	Cholinergic Agents (Cholinergics)IBA 01/2023 - 01/2013
7	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2021 - 04/2009
7	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2020 - 09/2004
6	Glycogen Synthase Kinase 3IBA 01/2013 - 05/2005
5	Phosphotransferases (Kinase)IBA 04/2022 - 08/2004
5	Protein Kinases (Protein Kinase)IBA 01/2020 - 04/2004
4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2023 - 01/2012
4	Peptides (Polypeptides)IBA 04/2022 - 12/2014
4	Peptide Hydrolases (Proteases)FDA Link 01/2021 - 01/2009
4	Protein Isoforms (Isoforms)IBA 01/2020 - 06/2011
4	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020 - 10/2015
4	Histones (Histone)IBA 01/2020 - 01/2017
4	CytokinesIBA 01/2019 - 07/2009
4	Synapsins (Synapsin I)IBA 11/2018 - 01/2012
4	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 12/2015 - 08/2004
4	Scopolamine (Hyoscine)FDA Link 10/2015 - 01/2013
4	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 03/2013 - 04/2003
3	Transcription Factors (Transcription Factor)IBA 04/2024 - 01/2018
3	SynucleinsIBA 02/2024 - 08/2017
3	Apolipoproteins E (ApoE)IBA 09/2023 - 03/2016
3	Folic Acid (Vitamin M)FDA LinkGeneric 04/2019 - 04/2009
3	ZincIBA 01/2018 - 03/2012
3	Neuroprotective AgentsIBA 01/2018 - 11/2017
3	Estrogens (Estrogen)FDA Link 03/2016 - 06/2008
3	SynaptophysinIBA 01/2015 - 01/2012
3	Acetylcarnitine (Alcar)IBA 01/2014 - 09/2011
3	WortmanninIBA 09/2008 - 02/2002
3	Neurofilament ProteinsIBA 06/2008 - 03/2002
3	calyculin AIBA 08/2007 - 04/2004
3	Protein Subunits (Protein Subunit)IBA 02/2007 - 08/2002
2	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 04/2006
2	Carrier Proteins (Binding Protein)IBA 12/2023 - 01/2015
2	MetalsIBA 12/2023 - 01/2020
2	Chelating AgentsIBA 12/2023 - 01/2018
2	Therapeutic UsesIBA 12/2023 - 01/2022
2	ApolipoproteinsIBA 09/2023 - 10/2021
2	Histone Deacetylases (Histone Deacetylase)IBA 10/2022 - 01/2020
2	Serine (L-Serine)FDA Link 01/2022 - 01/2014
2	Glycogen Synthase KinasesIBA 01/2022 - 07/2011
2	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2022 - 01/2014
2	SaltsIBA 01/2020 - 11/2017
2	Messenger RNA (mRNA)IBA 01/2020 - 06/2008
2	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 04/2019 - 01/2011
2	Insulin (Novolin)FDA Link 01/2019 - 03/2016
2	Sirtuin 1IBA 06/2018 - 04/2014
2	Fluoxetine (Prozac)FDA LinkGeneric 11/2017 - 01/2017
2	Small Interfering RNA (siRNA)IBA 12/2015 - 12/2013
2	JNK Mitogen-Activated Protein KinasesIBA 12/2015 - 10/2010
2	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 02/2015 - 01/2007
2	Streptozocin (Streptozotocin)FDA Link 01/2015 - 04/2014
2	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2009 - 04/2007
2	bisindolylmaleimide IIBA 09/2008 - 05/2005
2	Acetylcholine (Acetylcholine Chloride)FDA Link 09/2008 - 05/2008
2	Cytoskeletal ProteinsIBA 08/2007 - 04/2004
2	Peroxynitrous Acid (Peroxynitrite)IBA 07/2006 - 04/2005
1	Indicators and Reagents (Reagents)IBA 04/2024
1	Kelch-Like ECH-Associated Protein 1IBA 03/2024
1	CateninsIBA 03/2024
1	Cyclic AMP (AMP, Cyclic)IBA 12/2023
1	gypenoside IXIBA 12/2023
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 11/2023
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 02/2023

Therapy/Procedure

6	Therapeutics 01/2021 - 06/2013
3	Intraperitoneal Injections 05/2014 - 01/2013
1	Intravenous Administration 01/2024